32nd LISBON International Conference on Genetics, Cellular & Molecular Biology: LGCMB-26

Call for papers/Topics

Topics of Interest for Submission include, but are Not Limited to:

1. Molecular Biology 

This field focuses on the chemical and physical structures of biological macromolecules.

• Nucleic Acid Structure and Chemistry

  • DNA Double Helix (B-DNA, A-DNA, and Z-DNA).

  • RNA Varieties: mRNA, tRNA, rRNA, and non-coding RNAs (snRNA, snoRNA).

  • Epigenetic Modifications: DNA methylation and Histone acetylation.

• The Central Dogma & Beyond

  • Replication: Replication forks, telomeres, and proofreading mechanisms.

  • Transcription: Promoters, enhancers, and RNA Polymerase complexes.

  • Translation: Ribosome architecture, the Genetic Code, and tRNA charging.

  • Post-Transcriptional Processing: Splicing (introns/exons), 5' capping, and polyadenylation.

• Protein Synthesis & Folding

  • Chaperone proteins and proteasomes (protein degradation).

  • Post-translational modifications (Phosphorylation, Glycosylation, Ubiquitination).

2. Genetics

Genetics examines how information is passed across generations and how variation arises.

• Transmission (Mendelian) Genetics

  • Laws of Segregation and Independent Assortment.

  • Non-Mendelian patterns: Incomplete dominance, Co-dominance, and Pleiotropy.

  • Sex-linked inheritance and Pedigree analysis.

• Cytogenetics

  • Chromosome structure: Centromeres, Kinetochores, and Chromatin packing.

  • Karyotyping and Chromosomal aberrations (Aneuploidy, Translocations, Inversions).

• Molecular Genetics & Genomics

  • Gene mapping and Linkage analysis.

  • Genome sequencing (NGS) and Functional Genomics.

  • The structure of the Human Genome: Transposons, Pseudogenes, and Tandem repeats.

• Population & Evolutionary Genetics

  • Hardy-Weinberg Equilibrium.

  • Genetic Drift, Gene Flow, and Natural Selection at the molecular level.

  • Quantitative Genetics: Polygenic traits and Heritability.

3. Cellular Biology

Cell biology looks at the integrated functions of the cell as a living unit.

• Cell Membrane & Transport

  • Fluid Mosaic Model and Lipid Rafts.

  • Passive vs. Active Transport (Ion channels, symporters, and pumps).

  • Endocytosis, Exocytosis, and Autophagy.

• Organelle Function & Bioenergetics

  • Mitochondria and the Electron Transport Chain (ATP synthesis).

  • The Endomembrane System: ER, Golgi Apparatus, and Lysosomes.

  • Cytoskeletal Dynamics: Microtubules, Actin filaments, and Intermediate filaments.

• Cell Signaling (Signal Transduction)

  • Receptors: G-Protein Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs).

  • Second Messengers: cAMP, $Ca^{2+}$, and IP3/DAG.

  • Apoptosis (Programmed Cell Death) pathways.

• The Cell Cycle

  • Stages of Mitosis and Meiosis.

  • Checkpoints (G1, S, G2, M) and Cyclin-Dependent Kinases (CDKs).

  • Cancer Biology: Oncogenes and Tumor Suppressor genes (e.g., p53).

4. Major Interrelated Subtopics

These areas exist at the intersection of all three disciplines:

• Gene Expression Regulation: How a cell (Cell Bio) uses transcription factors (Molecular Bio) to determine which genes are active (Genetics).

• Recombinant DNA Technology & Biotechnology:

  • PCR (Polymerase Chain Reaction).

  • CRISPR-Cas9 Gene Editing.

  • Molecular Cloning and Viral Vectors.

• Developmental Biology: How genetic programs control cellular differentiation and morphogenesis from an embryo to an organism.

• Proteomics & Metabolomics: The large-scale study of proteins and metabolic byproducts that link the genome to the visible phenotype.

• Bioinformatics: Using computational tools to analyze the massive data sets generated by molecular and genetic research.